LOX and COX enzymes What are They?
LOX (Lipoxygenase) and COX (Cyclooxygenase) are enzymes in the body that process fatty acids like arachidonic acid (AA) and eicosapentaenoic acid (EPA) to create signaling molecules called eicosanoids. These molecules control inflammation, pain, immune response, and blood clotting.
Think of LOX and COX as factories that take in raw materials (fatty acids) and produce chemical messengers that tell the body how to respond to injury, infection, or other stimuli.
AA reacts with COX Enzyme (Cyclooxygenase) Produces PGE2 & TXA2
Prostaglandins (PGE2) → Causes pain, fever, inflammation.
Thromboxanes (TXA2) → Promotes blood clotting and blood vessel constriction.
AA Reacts with LOX Enzyme (Lipoxygenase) Produces LTB4
Leukotrienes (LTB4) → Strong immune activation and inflammation linked to asthma, allergic reactions, and autoimmune conditions.
EPA Reacts with COX Produces PGE3 & TXA3, Reacts with LOX Produces LTB5
PGE3, TXA3, and LTB5 are Weaker or even Anti-Inflammatory.
Phatma® 1440 Golden Bottle (5:1 EPA: DHA) delivers a high EPA content, per capsule contains over 1060mg EPA and over 210mg DHA ensuring optimal competition against AA at LOX and COX enzymes—reducing inflammatory roadblocks and promoting a smoother, healthier system.
